Medical Need

Acute Heart Failure & Renal Impairment

‘The majority of patients admitted with acute decompensated heart failure have significant renal impairment, which influences treatment and outcomes.’

Thomas Heywood et al; J Cardiac Fail 2007;13:422e430

 

Acute Heart Failure & Renal Impairment

‘The glomerular filtration rate is reduced in most patients with heart failure, especially if advanced, and renal function is a powerful independent predictor of prognosis in heart failure.’

ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012, European Heart Journal (2012) 33, 1787–1847

Acute Heart Failure & Renal Impairment

‘Persistence of congestion during hospitalisation is the most important prognostic factor associated with poor prognosis and outcome.’

 

Marco Metra et al, Circ Heart Fail. 2012;5:54-61

Acute Heart Failure & Renal Impairment

‘…24% of hospitalized for heart failure patients randomized in the United States were readmitted within 30 days of discharge despite the fact that the majority were treated with evidence-based treatments and had early postdischarge visits.’

 

Mihai Gheorghiade et al., JACC Vol. 61, No. 4, 2013: 391–403